WebMay 22, 2024 · The neurotrophin receptor (CD271/NGFR/p75NTR) is a key regulator of the melanocytic cell lineage through its ability to mediate cell growth, survival, and differentiation. Using clinical melanoma ... WebCD271 binds to the ligands NGF, BDNF, NTF3, and NTF4. CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, …
CD271 (NGF Receptor) Monoclonal Antibody …
WebCD271 serves as a receptor for the pro-forms of these neurotrophins and is differentiated from other members of the TNFR receptor family in that it binds pro and mature neurotrophins and affects the growth of the nervous system. Intramuscular p75(NTR) gene delivery impairs neovascularization and blood flow recovery in a mouse model of limb ... WebCD271 binds to the ligands NGF, BDNF, NTF3, and NTF4. CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, and RANBP9. The ME20.4 monoclonal antibody recognizes human, non-human primate, mouse, rat, sheep, rabbit, cat, dog, and pig CD271. brenthurst wealth management careers
4804 - Gene ResultNGFR nerve growth factor receptor [ (human)]
WebCD271 MicroBead Kits have been developed for the positive selection or depletion of cells expressing CD271 (LNGFR). They are ideally suited for the isolation of CD271+ mesenchymal stromal cells (MSCs) from human tissues, including bone marrow and lipoaspirate. In addition, CD271 MicroBead Kits have been used successfully for the … WebDec 1, 2024 · CD271 (NGFR) is a neurotrophin receptor that belongs to the tumor necrosis receptor (TNFR) family. Upon ligand binding, CD271 can mediate either survival or cell death. Although the role of CD271 as a marker of tumor-initiating cells is still a matter of debate, its role in melanoma progression has been well documented. WebCD271, also known as p75NTR, TNFRSF16, p75 (NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the ... brenthurst wealth mauritius