Phomopsidin
WebJun 29, 2004 · Read "First Total Synthesis of Antimitotic Compound, (+)‐Phomopsidin., ChemInform" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. WebDec 5, 2012 · The Journal of Antibiotics - Identification of a new phomoxanthone antibiotic from Phomopsis longicolla and its antimicrobial correlation with other metabolites during fermentation
Phomopsidin
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WebJun 1, 2024 · Phomopsidin, a known inhibitor of beta-tubulin that targets the eukaryotic cytoskeleton, inhibited the pathogen, but also showed mild cytotoxic effects. WebJan 20, 2003 · Phomopsidin and its (16Z)-isomer (MK8383) showed anti-microtubule activity at IC 50 of 5.7 and 8.0 μM, respectively, while the Me ester and other compounds were not active at 100 μM. The absolute configuration of phomopsidin ( 1 ) was …
WebPhomopsidin C21H30O3 CID 10381991 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … WebAbstract The absolute configuration of phomopsidin, a marine-derived fungal metabolite from Phomopsis sp. isolated at Pohnpei, was determined by the exciton chirality method as 6S, 7S, 8S, 11S, 12R, and 15R. The biosynthetic study using 13C-labeled precursors revealed the origin of all carbon atoms in phomopsidin, which was built by nine acetates and three …
WebSep 19, 2024 · It has been reported that the origin of carbons in phomopsidin ( 3) was built by nine acetates and three methyl groups from l -methionine by feeding experiment with 13 C-labeled precursors [25]. A similar biogenesis has also been proposed for carneic acids A and B [27] and lovastatin [28]. WebAbstract. (Equation presented) The first total synthesis of (+)-phomopsidin has been achieved via a diastereoselective transannular Diels-Alder (TADA) reaction. Key steps in …
WebDec 5, 2012 · The Journal of Antibiotics - Identification of a new phomoxanthone antibiotic from Phomopsis longicolla and its antimicrobial correlation with other metabolites during …
WebApr 24, 2024 · found to produce the anti-fungal beta-tubulin inhibitor phomopsidin in dual cul-ture with virulent strains of the pathogen. is compound was rst reported from a . iphone 13 price globe planWebFeb 19, 2004 · [reaction: see text] The first total synthesis of (+)-phomopsidin has been achieved via a diastereoselective transannular Diels-Alder (TADA) reaction. Key steps in the synthesis include diastereoselective ynone reduction with (-)-alpha-pinene and 9-BBN, macrocyclization by E-selective intramolecular … iphone 13 price brisbaneWebThey were isolated as major constituents of the stromata of Hypoxylon carneum, a species that had shown a highly specific secondary metabolite profile in a survey of xylariaceous ascomycetes based on HPLC profiling. Their chemical structures were elucidated by a combination of spectroscopic methods and by preparation of derivatives. iphone 13 price chartWebApr 24, 2024 · During a survey of xylarialean fungi in Northern Iran, several specimens that showed affinities to the Hypoxylon rubiginosum complex were collected and cultured. A comparison of their morphological characters, combined with a chemotaxonomic study based on high performance liquid chromatography, coupled with diode array detection … iphone 13 price in all countriesWebJan 24, 2009 · This manuscript describes an alternative synthetic approach for (+)-phomopsidin, which shows strong inhibitory activity against the assembly of microtubule proteins. We observed that the TADA... iphone 13 price greenWebThe absolute configuration of phomopsidin, a marine-derived fungal metabolite from Phomopsis sp. isolated at Pohnpei, was determined by the exciton chirality method as 6S, … iphone 13 price greeceWebPhomopsidin. Catalog No. T125428 CAS 199173-60-9. All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use. Phomopsidin, CAS 199173-60-9 Please contact us for prices and availability for the specification of product you are interested at. Product consultation. Get quote ... iphone 13 price in aptronix