Tfe3 molecular weight
Web28 May 2024 · The expression of TFE3 (transcription factor E3) in solitary fibrous tumours (SFTs) and their histologic mimickers was investigated, and the diagnostic value and clinical significance of TFE3... WebTranslocation-associated renal cell carcinoma (RCC) is a distinct subtype of RCC with gene rearrangements of the TFE3 or TFEB loci. The TFE3 gene is located at Xp11 and can fuse to a number of translocation partners, resulting in high nuclear expression of TFE3 protein. TFE3 immunostaining is often used as a surrogate marker for a TFE3 translocation. We …
Tfe3 molecular weight
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Web7 Feb 2024 · In wild-type hESC, TFE3 molecular weight (MW) increases from 72 to 80 kDa, as cells exit the naïve pluripotent stage (Fig. 4e, 10D TeSR). WebRecently, it has been shown that TFEB is a component of mammalian target of rapamycin (mTOR) complex 1 (mTORC1), which regulates the phosphorylation and nuclear translocation of TFEB in response to cellular starvation and stress (6-9). During normal growth conditions, TFEB is phosphorylated at Ser211 in an mTORC1-dependent manner.
Web18 Jan 2024 · CircMET has the potential to serve as a novel target for the molecular therapy of NONO-TFE3 tRCC as well as the other cancer with high-expressing circMET. Functions of CircMET (hsa_circ_0082002) which is a circular RNA and derived from MET gene remain understood incompletely. In the present study, Xp11.2 translocation/NONO-TFE3 fusion … WebAnti-TFE3 antibody (ab93808) Datasheet SDS Reviews ( 1) Submit a question References (7) Key features and details Rabbit polyclonal to TFE3 Suitable for: WB, IP Reacts with: …
WebReactivity: Human (QC Testing), Mouse (Tested in Development) Isotype: Mouse IgG1. Immunogen: TFE3-L Protein. Application: Western blot (Routinely Tested), Gel shift, Immunoprecipitation (Reported) Target Molecular Weight: 50 kDa. Concentration: 0.5 mg/ml. RRID: AB_395332. Storage Buffer: Aqueous buffered solution containing ≤0.09% … WebImmunohistochemistry for TFE3 protein has been considered by some to be a reliable surrogate for TFE3 molecular studies, although others disagree. We compared 2 methods …
WebTFE3 belongs to the MITF family of mammalian basic helix–loop–helix zipper transcription factors, together with TFEB and TFEC; all four can form homodimers or heterodimers with each other. 4 Embryonic expression of TFE3 orthologues Tfe3a and Tfe3b was demonstrated in the zebrafish in a wide range of tissues. 5 TFE3 subcellular localisation …
WebHGNC:11752 TFE3 MIM 301066 phenotype 314310 gene VEuPathDB HostDB:ENSG00000068323 neXtProt NX_P19532 Subcellular Location UniProt … free lean six sigma certification programsWebA biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields. Skip to main page content. HOME; ... Body weight did not differ between FLCN adipKO animals and controls (Supplemental Fig. 5A ). The relative ... TFE3 thus binds directly to the PGC-1β gene in the ... free lean six sigma green beltWeb19 Mar 2024 · Background NONO-TFE3 translocation renal cell carcinoma (NONO-TFE3 tRCC) is one subtype of RCCs associated with Xp11.2 translocation/TFE3 gene fusions RCC (Xp11.2 tRCCs). Long non-coding RNA (lncRNA) has attracted great attention in cancer research. The function and mechanisms of TRAF3IP2 antisense RNA 1 (TRAF3IP2-AS1), a … free lean six sigma training for militaryWeb5 May 2024 · Molecular Cancer Therapeutics December 17, 2014. Sunitinib is considered a first-line therapeutic option for patients with advanced clear cell renal cell carcinoma (ccRCC). Despite sunitinib's ... freelearn110Web30 Nov 2024 · BackgroundRenal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion is a rare and new subtype of RCC and was classified by the WHO in 2004. Since then, multiple 5′ fusion partners for TFE3 have been reported; however, the impact of individual fusion variant on specific clinicopathologic features of Xp11.2 … free lean six sigma toolsWeb19 Jan 2024 · Among primary malignant PEComas in this study, 86% had a TSC or TFE3 alteration. The authors proposed that molecular classification of myomelanocytic tumors should take precedence over, or at... bluefish outfittingWeb29 Dec 2010 · On the other hand, a moderate level of two TFE3 isoforms, with molecular weights of 72 kDa and 89 kDa, were detected in UOK257 and its sublines, and in 293FT cells. bluefish order